Job Description

Research Associate I -- On-site in Lexington, MA

Must be able to work on a W2

Job Summary:

As a Research Associate in the Nucleic Acid Delivery, Formulations & Bioanalysis department, you will become a part of a multinational and diverse team consisting of fellow Laboratory Technicians, Specialists/Scientists, and a global department manager. The goal of the team is to develop synthetic/non-viral nanomedicines, apply advanced analytical characterization techniques, and translate these to preclinical and clinical studies through internal and external collaborations.

Job Responsibilities:

• Regularly formulate and characterize lipid nanoparticles (LNPs) loaded with nucleic acids at small to mid-scale using microfluidics, ensuring reproducibility and scalability of the process while maintaining high product quality and consistency.
• Conduct freeze-drying studies to evaluate the stability of lipid nanoparticle (LNP) formulations, including assessing critical formulation parameters and optimizing freeze-drying cycles for maximum stability and efficacy of the final product.
• Communicate findings internally to the team via presentations and written reports.
• Independently plan, execute, and document experiments.

Job Qualifications:

• Bachelor’s degree strongly preferred with a minimum of 2 years of relevant experience OR high school diploma with 8+ years of relevant experience OR Associate or Vocational degree with 4+ years of relevant experience may also be considered.
• Relevant experience can be a combination of industry and academic experience and should include:
• Hands-on experience in formulating lipid nanoparticles at small to mid-scale using microfluidics.
• Hands-on experience in characterizing lipid nanoparticles loaded with nucleic acids (e.g., Ribogreen, DLS).
• Hands-on experience in lyophilization of lipid nanoparticles.
• Experience with analytical methods, including biophysical methods like dynamic light scattering (DLS), fluorescent-based assays (e.g., Ribogreen/PicoGreen), chromatography, pH, etc.
• Ability to independently operate good lab maintenance and equipment SOPs.
• Experience with automation.

Terms

• 12 month contract
• On-site in Lexington, MA
• Pay rate: $32-32/HR, $64,000-70,000 annually based on experience

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